Bypassing the Spinal Cord

Evidence for an alternative direct route of access for the scrapie agent to the brain bypassing the spinal cord.

Scrapie is a disease which occurs naturally in sheep and goats and belongs to a group of neurodegenerative disorders known as transmissible spongiform encephalopathies, or TSEs. There is currently no cure for TSEs, and the causative agent has not yet been identified. Numerous experiments, however, have addressed the pathogenetic process following a TSE infection. In this paper we present a stud...

Epidermal cyst in the spinal cord of a lamb

The Spinal Cord

The organizers of this conference got off to a good start by inviting investigators, both old and new, who have been engaged in the study of various aspects of cord neurophysiology, wisely restricting the field to the regions up to the medulla oblongata. The conference was almost unique in inviting papers on the morphology and histology of the cord, stressing the crucially important problem of ...

P 94: The Systemic Inflammation after Spinal Cord Injury

Spinal cord injury (SCI) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary mechanisms. Neuroinflammation is an important secondary injury process in SCI. The local inflammatory microenvironment within the injured spinal cord ...

Spinal cord

As part of the central nervous system (CNS), the spinal cord is the gateway for information transfer between body and brain, as well as a center for neuronal circuits that integrate and coordinate complex sensory, motor, and autonomic functions. This primer provides an overview of the organization and function of the mammalian spinal cord. With millions of neurons arising from eleven distinct p...